PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G77850.1
Common NameARF17, F28K19.6, T32E8.16
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ARF
Protein Properties Length: 585aa    MW: 63742 Da    PI: 5.6001
Description auxin response factor 17
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G77850.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B376.23.7e-24119220199
                  EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE.. CS
           B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefel 92 
                  f k+ltpsd+++ g +++p+ +a++       +++++  ++l ++d +g +W++++iyr++++r++lt+GW++Fv++++L +gD+vvF+  ++s  e+
  AT1G77850.1 119 FAKILTPSDANNGGGFSVPRFCADSVfpllnfQIDPPV-QKLYVTDIHGAVWDFRHIYRGTPRRHLLTTGWSKFVNSKKLIAGDSVVFM--RKSADEM 213
                  89*****************9999999*****9666655.49************************************************..4478889 PP

                  EEEEE-S CS
           B3  93 vvkvfrk 99 
                  +++v+r+
  AT1G77850.1 214 FIGVRRT 220
                  9***997 PP

2Auxin_resp89.46.5e-30274356183
   Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrl.sGtvvgvsdldpvrWpnSkWrsLk 83 
                  a+++as++ +Fevv++P a++seFvv++e+ve+++++ +++G+R+kma+etedss++++ +G+v+++ + ++  W++S+W++L+
  AT1G77850.1 274 AINRASQGLPFEVVFYPAAGWSEFVVRAEDVESSMSMYWTPGTRVKMAMETEDSSRITWfQGIVSSTYQ-ETGPWRGSPWKQLQ 356
                  67899******************************************************9999999999.888*********97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.101.5E-32112223IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019361.7E-27113225IPR015300DNA-binding pseudobarrel domain
PROSITE profilePS5086312.59119221IPR003340B3 DNA binding domain
SMARTSM010191.2E-20119221IPR003340B3 DNA binding domain
PfamPF023621.1E-21119220IPR003340B3 DNA binding domain
CDDcd100174.70E-20119215No hitNo description
PfamPF065072.7E-24274356IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009734Biological Processauxin-activated signaling pathway
GO:0010208Biological Processpollen wall assembly
GO:0048830Biological Processadventitious root development
GO:0052543Biological Processcallose deposition in cell wall
GO:0005634Cellular Componentnucleus
GO:0000987Molecular Functioncore promoter proximal region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020094anatomyplant egg cell
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 585 aa     Download sequence    Send to blast
MSPPSATAGD INHREVDPTI WRACAGASVQ IPVLHSRVYY FPQGHVEHCC PLLSTLPSST  60
SPVPCIITSI QLLADPVTDE VFAHLILQPM TQQQFTPTNY SRFGRFDGDV DDNNKVTTFA  120
KILTPSDANN GGGFSVPRFC ADSVFPLLNF QIDPPVQKLY VTDIHGAVWD FRHIYRGTPR  180
RHLLTTGWSK FVNSKKLIAG DSVVFMRKSA DEMFIGVRRT PISSSDGGSS YYGGDEYNGY  240
YSQSSVAKED DGSPKKTFRR SGNGKLTAEA VTDAINRASQ GLPFEVVFYP AAGWSEFVVR  300
AEDVESSMSM YWTPGTRVKM AMETEDSSRI TWFQGIVSST YQETGPWRGS PWKQLQITWD  360
EPEILQNVKR VNPWQVEIAA HATQLHTPFP PAKRLKYPQP GGGFLSGDDG EILYPQSGLS  420
SAAAPDPSPS MFSYSTFPAG MQGARQYDFG SFNPTGFIGG NPPQLFTNNF LSPLPDLGKV  480
STEMMNFGSP PSDNLSPNSN TTNLSSGNDL VGNRGPLSKK VNSIQLFGKI ITVEEHSESG  540
PAESGLCEED GSKESSDNET QLSLSHAPPS VPKHSNSNAG SSSQG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldw_B3e-612037723353Auxin response factor 1
4ldw_A3e-612037723353Auxin response factor 1
4ldv_A3e-612037723353Auxin response factor 1
4ldx_B3e-612037723353Auxin response factor 1
4ldx_A3e-612037723353Auxin response factor 1
4ldy_B3e-612037723353Auxin response factor 1
4ldy_A3e-612037723353Auxin response factor 1
4ldu_A7e-611637751388Auxin response factor 5
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible262136_at0.0
Expression AtlasAT1G77850-
AtGenExpressAT1G77850-
ATTED-IIAT1G77850-
Functional Description ? help Back to Top
Source Description
TAIRPosttranscriptionally regulated by miR160 and is essential for proper development.Regulates early auxin response genes.
UniProtAuxin response factors (ARFs) are transcriptional factors that binds specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Function -- GeneRIF ? help Back to Top
  1. Phenotypic plasticity of adventitious rooting is controlled by complex regulation of AUXIN RESPONSE FACTOR transcripts and microRNA abundance. ARF17, a target of miR160, is a negative regulator.
    [PMID: 19820192]
  2. ARF17 is essential for pollen wall patterning in Arabidopsis by modulating primexine formation at least partially through direct regulation of CalS5 gene expression.
    [PMID: 23580594]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G77850.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT4G27260(R), AT5G54510(R)
Regulation -- MicroRNA ? help Back to Top
Source Description
miRTarBaseRegulated by ath-miR160c, ath-miR160b, ath-miR160a
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDauxin
Interaction ? help Back to Top
Source Intact With
IntActSearch Q84WU6
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G77850
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0027490.0BT002749.1 Arabidopsis thaliana clone C104833 auxin response factor ARF17 (At1g77850) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_565161.10.0auxin response factor 17
SwissprotQ84WU60.0ARFQ_ARATH; Auxin response factor 17
TrEMBLD7KV470.0D7KV47_ARALL; Auxin response factor
STRINGAT1G77850.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58027130
Representative plantOGRP5261578
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Hagen G,Guilfoyle T
    Auxin-responsive gene expression: genes, promoters and regulatory factors.
    Plant Mol. Biol., 2002 Jun-Jul. 49(3-4): p. 373-85
    [PMID:12036261]
  3. Kasschau KD, et al.
    P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA unction.
    Dev. Cell, 2003. 4(2): p. 205-17
    [PMID:12586064]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Vazquez F,Gasciolli V,Cr
    The nuclear dsRNA binding protein HYL1 is required for microRNA accumulation and plant development, but not posttranscriptional transgene silencing.
    Curr. Biol., 2004. 14(4): p. 346-51
    [PMID:14972688]
  6. Vaucheret H,Vazquez F,Cr
    The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development.
    Genes Dev., 2004. 18(10): p. 1187-97
    [PMID:15131082]
  7. Remington DL,Vision TJ,Guilfoyle TJ,Reed JW
    Contrasting modes of diversification in the Aux/IAA and ARF gene families.
    Plant Physiol., 2004. 135(3): p. 1738-52
    [PMID:15247399]
  8. Souret FF,Kastenmayer JP,Green PJ
    AtXRN4 degrades mRNA in Arabidopsis and its substrates include selected miRNA targets.
    Mol. Cell, 2004. 15(2): p. 173-83
    [PMID:15260969]
  9. Hass C, et al.
    The response regulator 2 mediates ethylene signalling and hormone signal integration in Arabidopsis.
    EMBO J., 2004. 23(16): p. 3290-302
    [PMID:15282545]
  10. Okushima Y, et al.
    Functional genomic analysis of the AUXIN RESPONSE FACTOR gene family members in Arabidopsis thaliana: unique and overlapping functions of ARF7 and ARF19.
    Plant Cell, 2005. 17(2): p. 444-63
    [PMID:15659631]
  11. Mallory AC,Bartel DP,Bartel B
    MicroRNA-directed regulation of Arabidopsis AUXIN RESPONSE FACTOR17 is essential for proper development and modulates expression of early auxin response genes.
    Plant Cell, 2005. 17(5): p. 1360-75
    [PMID:15829600]
  12. Sorin C, et al.
    Auxin and light control of adventitious rooting in Arabidopsis require ARGONAUTE1.
    Plant Cell, 2005. 17(5): p. 1343-59
    [PMID:15829601]
  13. Axtell MJ,Bartel DP
    Antiquity of microRNAs and their targets in land plants.
    Plant Cell, 2005. 17(6): p. 1658-73
    [PMID:15849273]
  14. Wang JW, et al.
    Control of root cap formation by MicroRNA-targeted auxin response factors in Arabidopsis.
    Plant Cell, 2005. 17(8): p. 2204-16
    [PMID:16006581]
  15. Siemens J, et al.
    Transcriptome analysis of Arabidopsis clubroots indicate a key role for cytokinins in disease development.
    Mol. Plant Microbe Interact., 2006. 19(5): p. 480-94
    [PMID:16673935]
  16. Wu F, et al.
    The N-terminal double-stranded RNA binding domains of Arabidopsis HYPONASTIC LEAVES1 are sufficient for pre-microRNA processing.
    Plant Cell, 2007. 19(3): p. 914-25
    [PMID:17337628]
  17. Lewsey M,Robertson FC,Canto T,Palukaitis P,Carr JP
    Selective targeting of miRNA-regulated plant development by a viral counter-silencing protein.
    Plant J., 2007. 50(2): p. 240-52
    [PMID:17444907]
  18. Goeres DC, et al.
    Components of the Arabidopsis mRNA decapping complex are required for early seedling development.
    Plant Cell, 2007. 19(5): p. 1549-64
    [PMID:17513503]
  19. Axtell MJ,Snyder JA,Bartel DP
    Common functions for diverse small RNAs of land plants.
    Plant Cell, 2007. 19(6): p. 1750-69
    [PMID:17601824]
  20. Gifford ML,Dean A,Gutierrez RA,Coruzzi GM,Birnbaum KD
    Cell-specific nitrogen responses mediate developmental plasticity.
    Proc. Natl. Acad. Sci. U.S.A., 2008. 105(2): p. 803-8
    [PMID:18180456]
  21. Ehrenreich IM,Purugganan MD
    Sequence variation of MicroRNAs and their binding sites in Arabidopsis.
    Plant Physiol., 2008. 146(4): p. 1974-82
    [PMID:18305205]
  22. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  23. Swaminathan K,Peterson K,Jack T
    The plant B3 superfamily.
    Trends Plant Sci., 2008. 13(12): p. 647-55
    [PMID:18986826]
  24. Gutierrez L, et al.
    Phenotypic plasticity of adventitious rooting in Arabidopsis is controlled by complex regulation of AUXIN RESPONSE FACTOR transcripts and microRNA abundance.
    Plant Cell, 2009. 21(10): p. 3119-32
    [PMID:19820192]
  25. Wuest SE, et al.
    Arabidopsis female gametophyte gene expression map reveals similarities between plant and animal gametes.
    Curr. Biol., 2010. 20(6): p. 506-12
    [PMID:20226671]
  26. Varaud E, et al.
    AUXIN RESPONSE FACTOR8 regulates Arabidopsis petal growth by interacting with the bHLH transcription factor BIGPETALp.
    Plant Cell, 2011. 23(3): p. 973-83
    [PMID:21421811]
  27. Vernoux T, et al.
    The auxin signalling network translates dynamic input into robust patterning at the shoot apex.
    Mol. Syst. Biol., 2011. 7: p. 508
    [PMID:21734647]
  28. Causier B,Ashworth M,Guo W,Davies B
    The TOPLESS interactome: a framework for gene repression in Arabidopsis.
    Plant Physiol., 2012. 158(1): p. 423-38
    [PMID:22065421]
  29. Reňák D,Dupl'áková N,Honys D
    Wide-scale screening of T-DNA lines for transcription factor genes affecting male gametophyte development in Arabidopsis.
    Sex. Plant Reprod., 2012. 25(1): p. 39-60
    [PMID:22101548]
  30. Gutierrez L, et al.
    Auxin controls Arabidopsis adventitious root initiation by regulating jasmonic acid homeostasis.
    Plant Cell, 2012. 24(6): p. 2515-27
    [PMID:22730403]
  31. Yang J, et al.
    AUXIN RESPONSE FACTOR17 is essential for pollen wall pattern formation in Arabidopsis.
    Plant Physiol., 2013. 162(2): p. 720-31
    [PMID:23580594]
  32. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]